Injectable HIV treatment only requires six doses per year, study finds
ViiV Healthcare's monthly injections are just as effective every two months, company announces
Monthly injections to treat HIV are as effective when used every two months, according to new findings.
ViiV Healthcare, a specialist HIV company which is part of GlaxoSmithKline, earlier this year achieved FDA approval for Cabenuva, a monthly injectable antiretroviral regimen to treat HIV.
The monthly injections were touted for their ability to reduce treatment for the virus from a daily pill regimen to just 12 treatment days per year.
Now, ViiV has announced that Cabenuva — a combination of two antiretroviral injections, ViiV’s cabotegravir and Johnson & Johnson’s rilpivirine — can achieve similar levels of performance when administered every two months.
“It provides an option that could change the treatment experience for some people living with HIV by removing the need for daily pills for the treatment of HIV,” Hans Jäeger, MD, investigator for ViiV’s ATLAS-2M study, said in a statement.
“Taking a pill every day can come as an unwelcome daily reminder of their HIV status or it may add to their fears that their HIV status might be disclosed by someone seeing their HIV medication,” Jäeger continued. “This regimen can enable people living with HIV to reduce the days they receive treatment from 365 to 12 or 6 per year, representing a paradigm shift in their experience of HIV treatment.”
Data from ViiV’s global study confirmed that dosing the treatment every two months was “non-inferior to monthly dosing,” the company said.
Read More: Study finds having undetectable HIV levels “effectively prevents” transmission among gay couples
ViiV had previously examined two-month dosing’s efficacy up to 48 weeks, finding it to be “similarly effective” to monthly dosing. After 96 weeks, ViiV’s data showed “that rates of virologic suppression were similar between the two arms” of the study.
The company has now submitted a supplemental New Drug Application to the FDA to expand the use of Cabenuva to include both monthly and two-monthly dosing.
In addition to its use in Cabenuva, ViiV has previously found that bi-monthly injections of its antiretroviral cabotegravir are more effective when used as PrEP than once-daily pills.
Read More: PrEP injection every two months proves more effective than daily Truvada
Sold under the brand name Truvada, PrEP — or pre-exposure prophylaxis — is a single, daily pill that uses antiretrovirals to help prevent HIV-negative people from contracting the virus.
While the pill is already up to 99% effective at preventing transmission of HIV, ViiV found that an injection of cabotegravir every two months was even more effective — 69% more — at preventing transmission.
Related:
Congressional HIV/AIDS Caucus introduces bill to stop criminalizing people with HIV
Anti-LGBTQ televangelist: Gay men have “secret ring” to transmit HIV through handshakes
DC offers COVID vaccine to people with chronic health conditions, including HIV
Read More:
Utah Republican rants that leftists ‘won’t be happy until we are all bisexual’
Barack Obama joked about Pete Buttigieg being “gay” and “short” new book claims
Transgender lawmakers condemn Tuberville Amendment, urge passage of Equality Act
Support Metro Weekly’s Journalism
These are challenging times for news organizations. And yet it’s crucial we stay active and provide vital resources and information to both our local readers and the world. So won’t you please take a moment and consider supporting Metro Weekly with a membership? For as little as $5 a month, you can help ensure Metro Weekly magazine and MetroWeekly.com remain free, viable resources as we provide the best, most diverse, culturally-resonant LGBTQ coverage in both the D.C. region and around the world. Memberships come with exclusive perks and discounts, your own personal digital delivery of each week’s magazine (and an archive), access to our Member's Lounge when it launches this fall, and exclusive members-only items like Metro Weekly Membership Mugs and Tote Bags! Check out all our membership levels here and please join us today!
You must be logged in to post a comment.